Yogita Chudasama

Associate Professor

Stewart Biological Sciences Bldg.
Room N8/4, 514-398-3419
yogita.chudasama at mcgill.ca

Chudasama Laboratory of Brain and Behaviour

Research Areas

Behavioral Neuroscience

Research Summary

Professor Chudasama’s research integrates methods of behaviour, neuroanatomy and psychopharmacology to understand the neurobiological mechanisms underlying processes of learning, memory and attention. Her main work focuses on the executive functions of the frontal lobe and its interaction with the medial temporal lobe. She is particularly interested in how neurochemical pathology of the fronto-temporal circuitry can affect normal cognitive and emotional behaviour. This work is guided by fundamental scientific questions but also is designed to have potential application to neuropsychiatric disorders, specifically in the area of developing therapeutic treatments for such disorders as schizophrenia, depression, and attention deficit hyperactivity disorder.

Professor Chudasama's laboratory is affiliated with the Center for Studies in Behavioral Neurobiology (CSBN).

Selected References

Abela AR, Chudasama Y. Noradrenergic a2a-receptor stimulation of the ventral hippocampus modulates impulsive decision-making. Psychopharmacology. In press.

Prasad JA, Chudasama Y. (2013) Viral tracing identifies parallel disynaptic pathways to the hippocampus. Journal of Neuroscience 33:8494-8503.

Abela AR, Dougherty SD, Fagen ED, Hill CJR, Chudasama Y. (2013) Inhibitory control deficits in rats with ventral hippocampal lesions. Cerebral Cortex 23:1396-1409

Chudasama Y, Daniels TE, Gorrin DP, Rhodes SEV, Rudebeck PH, Murray EA (2012) The role of anterior cingulate cortex in choices based on reward value and reward contingency. Cerebral Cortex (in press)

Abela AR, Chudasama Y (2013) Dissociable contributions of the ventral hippocampus and orbitofrontal cortex to decision-making with a delayed or uncertain outcome. European Journal of Neuroscience 37: 640-647.

Chudasama Y, Doobay VM, Liu Y. (2013) Hippocampal-prefrontal cortical circuit mediates inhibitory response control in the rat. Journal of Neuroscience 32: 10915-10924.

Prasad JA, Macgregor EM, Chudasama Y. (2013) Lesions of the thalamic reuniens cause impulsive but not compulsive responses. Brain, Structure and Function 218: 85-96.

Chudasama Y. (2011) Animal models of prefrontal-executive function. Behavioural Neuroscience 3:327-343. 

Chudasama Y, Izquierdo A, Murray EA. (2009) Distinct contribution of the amygdala and hippocampus to fear expression. European Journal of Neuroscience 30: 2327-2337. 

Chudasama Y, Wright KS, Murray EA. (2008) Hippocampal lesions in rhesus monkeys disrupt emotional responses but not reinforcer devaluation effects. Biological Psychiatry 63:1084-1091. 

Updated: October 2013
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