Michael W. Salter, M.D., Ph.D. (University of Toronto)



Michael Salter is one of world's foremost pain researchers, with expertise in cellular signaling mechanisms underlying chronic pain. Mike and Jeff are have collaborated on a very interesting sex difference involving neuroimmune control of chronic pain. 


  • Sorge, R.E., LaCroix-Fralish, M.L., Tuttle, A.H., Sotocinal, S.G., Austin, J.-S., Ritchie, J., Chanda, M.L., Graham, A.C., Topham, L., Beggs, S., Salter, M.W., and Mogil, J.S. Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice.  J. Neurosci., 31:15450-15454, 2011.

  • Sorge, R.E., Trang, T., Dorfman, R., Smith, S.B., Beggs, S., Ritchie, J., Austin, J.-S., Zaykin, D.V., Vander Meulen, H., Costigan, M., Herbert, T.A., Yarkoni-Abitbul, M., Tichauer, D., Livneh, J., Gershon, E., Zheng, M., Tan, K., John, S.L., Slade, G.D., Jordan, J., Woolf, C.J., Peltz, G., Maixner, W., Diatchenko, L., Seltzer, Z., Salter, M.W. and Mogil, J.S.  Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.  Nat. Med., 18:595-599, 2012.
  • Cahill, L.S., Laliberte, C.L., Liu, X.J., Bishop, J., Nieman, B.J., Mogil, J.S., Sorge, R.E., Jones, C.D., Salter, M.W., and Henkelman, R.M.  Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse.  Mol. Pain, 10:60, 2014.

  • Sorge, R.E., Mapplebeck, J.C.S., Rosen, S., Beggs, S., Taves, S., Alexander, J.K., Martin, L.J., Austin, J.-S., Sotocinal, S.G., Chen, D., Yang, M., Shi, X.Q., Huang, H., Pillon, N.J., Bilan, P.J., Tu, Y., Klip, A., Ji, R.-R., Zhang, J., Salter, M.W. and Mogil, J.S.  Different immune cells mediate mechanical pain hypersensitivity in male and female mice.  Nat. Neurosci., 18:1081-103, 2015.
  • Mapplebeck, J.C.S., Dalgarno, R., Tu, Y., Moriarty, O., Beggs, S., Kwok, C.H.T., Halievski, K., Assi, S., Mogil, J.S., Trang, T., and Salter, M.W. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Pain, in press.

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