Original Papers

Clarivate Highly Cited Paper (top 1% of field for its age):  ♥

Clarivate Web of Science citations to date:  †20+, ††50+, †††100+, ††††200+, †††††500+

Altmetric score:  ◊20+, ◊◊50+, ◊◊◊100+, ◊◊◊◊200+, ◊◊◊◊◊500+

 

  • Lister, K.C., Maldonado Bouchard, S., Markova, T., Aternali, A., Denecli, P., Donayre Pimentel, S., Majeed, M., Austin, J.-S., Williams, A.C.deC., and Mogil, J.S.  Chronic pain produces hypervigilance to predator odor in mice.  Curr. Biol., 30:R866-R867, 2020.   (DOI:  10.1016/j.cub.2020.06.025) ◊

  • Muralidharan, A., Sotocinal, S.G., Austin, J.-S., and Mogil, J.S.  The influence of aging and duration of injury on the anti-allodynic efficacy of analgesics in laboratory mice.  Pain Rep., 5:e824, 2020.  (DOI: 10.1097/PR9.0000000000000824)
  • Linnstaedt, S.D., Rueckeis, C.A., Riker, K.D., Pan, Y., Wu, A., Yu, S., Wanstrath, B., Gonzalez, M., Harmon, E., Green, P., Chen, C., King, T., Lewandowski, C., Hendry, P.L., Pearson, C., Kurz, M.C., Datner, E., Velilla, M.A., Domeier, R., Liberzon, I., Mogil, J.S., Levine, J., and McLean, S.A.  microRNA-19b predicts widespread pain and posttraumatic stress symptom risk in a sex-dependent manner following trauma exposure.  Pain, 161:47?60, 2020.   (DOI:  10.1097/j.pain.0000000000001709)
  • Petitjean, H., Bourojeni, F.B., Tsao, D., Davidova, A., Sotocinal, S.G., Mogil, J.S., Kania, A., and Sharif-Naeini, R.  Recruitment of spinoparabrachial neurons by dorsal horn calretinin neurons.  Cell Rep., 28:1429-1438, 2019.   (DOI:  10.1016/j.celrep.2019.07.048)
  • Parisien, M., Samoshkin, A., Tansley, S.N., Piltonen, M.H., Martin, L.J., El-Hachem, N., Dagostino, C., Allegri, M., Mogil, J.S., Khoutorsky, A., and Diatchenko, L.  Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain.  Pain, 160:932-944, 2019.   (DOI:  10.1097/j.pain.0000000000001471)
  • Tansley, S.N., Macintyre, L.C., Diamond, L., Sotocinal, S.G., George, N., Meluban, L., Austin, J.-S., Coderre, T.J., Martin, L.J., and Mogil, J.S.  Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity.  Pain, 160:784-792, 2019.  (DOI:  10.1097/j.pain.0000000000001454)
  • Smith, S.B., Parisien, M., Bair, E., Belfer, I., Chabot-Dore, A.-J., Gris, P., Khoury, S. Tansley, S., Torosyan, Y., Zaykin, D.V., Bernhardt, O., de Oliveira Serrano, P., Gracely, R.H., Jain, D., Jarvelin, M.-R., Kaste, L.M., Kerr, K.F., Kocher, T., Lahdesmaki, R., Laniado, N., Laurie, C.C., Laurie, C.A., Mannikko, M., Meloto, C.B., Nackley, A.G., Nelson, S.C., Pesonen, P., Ribeiro-Dasilva, M.C., Rizzatti-Barbosa, C.M., Sanders, A.E., Schwahn, C., Sipila, K., Sofer, T., Teumer, A., Mogil, J.S., Fillingim, R.B., Greenspan, J.D., Ohrbach, R., Slade, G.D., Maixner, W., and Diatchenko, L.  Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males.  Pain, 160:579-591, 2019.   (DOI:  10.1097/j.pain.0000000000001438)
  • Martin, L.J., Acland, E.L., Cho, C., Gandhi, W., Chen, D., Corley, E., Kadoura, B., Levy, T., Mirali, S., Tohyama, S., Khan, S., MacIntyre, L.C., Carlson, E.N., Schweinhardt, P., and Mogil, J.S.  Male-specific conditioned pain hypersensitivity in mice and humans.   Curr. Biol., 29:192-201.e4, 2019.   (DOI:  10.1016/j.cub.2018.11.030) ◊◊◊◊
  • Rosen, S., Ham, B., Haichin, M., Walters, I., Tohyama, S., Sotocinal, S.G., and Mogil, J.S.  Increased pain sensitivity and decreased opioid analgesia in T cell-deficient mice and implications for sex differences.  Pain, 160:358-366, 2019.  (DOI:  10.1097/j.pain.0000000000001420)
  • Baskozos, G., Dawes, J.M., Austin, J.S., Antunes-Martins, A., McDermott, L., Clark, A.J., McMahon, S.B., Mogil, J.S., Orengo, C., and Bennett, D.L.  Comprehensive analysis of long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury.  Pain, 160:463-485, 2019. (DOI:  10.1097/j.pain.0000000000001416)
  • Tansley, S.N., Tuttle, A.H., Wu, N., Tohyama, S., Dossett, K., Gerstein, L., Ham, B., Austin, J.-S., Sotocinal, S.G., and Mogil, J.S.  Modulation of social behavior and dominance status by chronic pain in mice.  Genes Brain Behav., 18:e12514, 2019.   (DOI:  10.1111/gbb.12514)
  • Mapplebeck, J.C.S., Dalgarno, R., Tu, Y.S., Moriarty, O., Beggs, S., Kwok, C.H.T., Halievski, K., Assi, S., Mogil, J.S., Trang, T., and Salter, M.W.  Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats.  Pain, 159:1752-1763, 2018.  (DOI:  10.1097/j.pain.0000000000001265)
  • Uttam, S., Wong, C., Amorim, I.S., Jafarnejad, S.M., Tansley, S.N., Yang, J., Prager?Khoutorsky, M., Mogil, J.S., Gkogkas, C.G., and Khoutorsky, A.  Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain.  Neurobiol. Pain, 4:35-44, 2018.  (DOI:  10.1016/j.ynpai.2018.04.001)
  • Tuttle, A.H., Molinaro, M.J., Jethwa, J.F., Sotocinal, S.G., Prieto, J.C., Styner, M.A., Mogil, J.S., and Zylka, M.J.  A deep neural network to assess spontaneous pain from mouse facial expressions.  Mol. Pain, 14:1-29, 2018.  (DOI:  10.1177/1744806918763658) †◊
  • Rosen, S.F., Ham, B., Drouin, S., Boachie, N., Chabot-Dore, A.-J., Austin, J.-S., Diatchenko, L., and Mogil, J.S.  T cell mediation of pregnancy analgesia affecting chronic pain in mice.   J. Neurosci., 37:9819-9827, 2017.   (DOI:  10.1523/JNEUROSCI.2053-17.2017)
  • Martin, L.J., Smith, S.B., Khoutorsky, A., Magnussen, C.A., Samoshkin, A., Sorge, R.E., Cho, C., Yosefpour, N., Sivaselvachandran, S., Tohyama, S., Cole, T., Khong, T.M., Mir, E., Gibson, D.G., Wieskopf, J.S., Sotocinal, S.G., Austin, J.-S., Meloto, C.B., Gitt, J.H., Gkogkas, C., Sonenberg, N., Greenspan, J., Fillingim, R.B., Ohrbach, R., Slade, G.D., Knott, C., Dubner, R., Nackley, A.G., Ribeiro-da-Silva, A., Neely, G.G., Maixner, W., Zaykin, D.V., Mogil, J.S.*, and Diatchenko, L.*  Epiregulin and EGFR interactions are involved in pain processing.  J. Clin. Invest., 127:3353-3363, 2017.   (*co-corresponding authors)   (DOI:  10.1172/JCI87406) †◊◊◊◊
  • Moy, J.K., Khoutorsky, A., Asiedu, M.N., Black, B.J., Kuh, J.L., Barragan-Iglesias, P., Megat, S., Burton, M.D., Burgos-Vega, C.C., Melemedjian, O.K., Boitano, S., Vagner, J., Gkogkas, C.G., Pancrazio, J.J., Mogil, J.S., Dussor, G., Sonenberg, N., and Price, T.J.     The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain.  J. Neurosci., 37:7481-7499, 2017.   (DOI:  10.1523/JNEUROSCI.0220-17.2017)
  • Parisien, M., Khoury, S., Chabot-Dore, A.-J., Sotocinal, S.G., Slade, G.D., Smith, S.B., Fillingim, R.B., Ohrbach, R., Greenspan, J.D., Maixner, W., Mogil, J.S., Belfer, I., and Diatchenko, L.  Effect of human genetic variability on gene transcription in dorsal root ganglia and association with pain phenotypes.  Cell Rep., 19:1940-1952, 2017.   (DOI:  10.1016/j.celrep.2017.05.018)
  • Tuttle, A.H., Tansley, S., Dossett, K., Tohyama, S., Khoutorsky, A., Maldonado-Bouchard, S., Stein, L., Gerstein, L., Crawhall-Duk, H., Pearl, R., Sukosd, M., Leger, P., Hardt, O., Yachnin, D., Austin, J.-S., Chan, C.M., Groves, I., Pooters, T., Martin, L.J., Sonenberg, N., Gkogkas, C.G., and Mogil, J.S.  Social propinquity in rodents as measured by tube co?occupancy differs between inbred and outbred genotypes.  Proc. Natl. Acad. Sci. U.S.A., 114:5515-5520, 2017.  (DOI:  10.1073/pnas.1703477114)
  • Khoutorsky, A., Sorge, R.E., Prager-Khoutorsky, M., Pawlowski, S.A., Longo, G., Jafarnejad, S.M., Tahmasebi, S., Martin, L.J., Pitcher, M.H., Gkogkas, C.G., Sharif-Naeini, R., Ribeiro-da-Silva, A., Bourque, C.W., Cervero, F., Mogil, J.S.*, and Sonenberg, N.*  eIF2a phosphorylation controls thermal nociception.  Proc. Natl. Acad. Sci., U.S.A., 113:11949-11954, 2016.  (*co-corresponding authors)   (DOI:  10.1073/pnas.1614047113)
  • Ultsch, A., Kringel, D., Kalso, E., Mogil, J.S., and Lotsch, J.  A data science approach to candidate gene selection of pain regarded as a process of learning and neural plasticity.  Pain, 157:2747-2757, 2016.   (DOI: 10.1097/j.pain.0000000000000694)
  • Kikusui, T., Ishio, Y., Nagasawa, M., Mogil, J.S., and Mogi, K.  Early weaning impairs a social contagion of pain-related stretching behavior in mice.  Dev. Psychobiol., 58:1101-1107, 2016.  (DOI:  10.1002/dev.21443)
  • Young, E., Bryant, C., Lee, S., Nair, H., Dreher, K., Zhang, X., Palmer, A., Chung, J.M., Mogil, J.S., Chesler, E., and Lariviere, W.  Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test.  Genes Brain Behav., 15:604-615, 2016.   (DOI:  10.1111/gbb.12302) ◊◊◊
  • Kahle, K.T., Schmouth, J.F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Omura, T., Laganiere, J., Rochefort, D., Hince, P., Castonguay, G., Gaudet, R., Mapplebeck, J.C., Sotocinal, S.G., Duan, J., Ward, C., Khanna, A.R., Mogil, J.S., Dion, P.A., Woolf, C.J., Inquimbert, P., and Rouleau, G.A.  Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition.  Sci. Signal. 9:ra32, 2016.   (DOI:  10.1126/scisignal.aad0163)†
  • Daou, I., Beaudry, H., Ase, A.R., Wieskopf, J.S., Ribeiro-da-Silva, A., Mogil, J.S., and Seguela, P.  Optogenetic silencing of Nav1.8-positive afferents alleviates inflammatory and neuropathic pain.  eNeuro, 3: e0140-15.2016, 2016.   (DOI:  10.1523/ENEURO.0140-15.2016) †◊◊◊
  • Samoshkin, A., Convertino, M., Viet, C.T., Wieskopf, J.S., Marcovitz, J., Patel, P., Stone, L., Maixner, W., Mogil, J.S., Schmidt, B.L., Dokholyan, N.V., and Diatchenko, L.  Structural and functional interaction between six transmembrane m-opioid receptor isoform and b2-adrenoceptors.  Sci. Rep., 5:18198, 2015.   (DOI:  10.1038/srep18198)

  • Khoutorsky, A., Bonin, R.P., Sorge, R.E., Gkogkas, C., Pawlowski, S.A., Jafarnejad, S.M., Pitcher, M.H., Alain, T., Perez-Sanchez, J. Salter, E.W., Martin, L.J., Ribeiro-da-Silva, A., De Koninck, Y., Cervero, F., Mogil, J.S.* and Sonenberg, N.*  Translational control of nociception via 4E-binding protein 1.  eLife, 4:e12002, 2015.  (DOI:  10.7554/eLife.12002)       (*co-corresponding authors)
  • Martin, L.J., Piltonen, M.H., Gauthier, J., Convertino, M., Acland, E.L., Dokholyan, N.V., Mogil, J.S., Diatchenko, L., and Maixner, W.  Differences in the antinociceptive effects and binding properties of propranolol and bupranolol enantiomers.  J. Pain, 16:1321-1333, 2015.   (DOI:  10.1016/j.jpain.2015.09.004)
  • Sorge, R.E., Mapplebeck, J.C.S., Rosen, S., Beggs, S., Taves, S., Alexander, J.K., Martin, L.J., Austin, J.-S., Sotocinal, S.G., Chen, D., Yang, M., Shi, X.Q., Huang, H., Pillon, N.J., Bilan, P.J., Tu, Y., Klip, A., Ji, R.-R., Zhang, J., Salter, M.W. and Mogil, J.S.  Different immune cells mediate mechanical pain hypersensitivity in male and female mice.  Nat. Neurosci., 18:1081-1083, 2015.  (DOI:  10.1038/nn.4053) ♥††††◊◊◊◊◊
  • Segall, S.K., Shabalina, S.A., Meloto, C.B., Wen, X., Gauthier, J., Wiltshire, T., Cunningham, D., Tarantino, L., Tohyama, S., Martin, L.J., Mogil, J.S., and Diatchenko, L.  Molecular genetic mechanisms of allelic specific regulation of murine Comt expression.  Pain, 156:1965-1977, 2015.   (DOI:  10.1097/j.pain.0000000000000258)

  • Wieskopf, J.S., Mathur, J. Limapichat, W., Post, M.R., Al-Qazzaz, M., Sorge, R.E., Martin, L.J., Zaykin, D.V., Smith, S.B., Freitas, K., Austin, J.-S., Dai, F., Zhang, J., Marcovitz, J., Tuttle, A.H., Slepian, P.M., Clarke, S., Drenan, R.M., Janes, J., Al Sharari, S., Segall, S.K., Aasvang, E.K., Lai, W., Bittner, R., Richards, C.I., Slade, G.D., Kehlet, H., Walker, J., Maskos, U., Changeux, J.-P., Devor, M., Maixner, W., Diatchenko, L., Belfer, I., Dougherty, D.A., Su, A.I., Lummis, S.C.R., Damaj, M.I., Lester, H.A., Patapoutian, A., and Mogil, J.S.  The nicotinic a6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.  Sci. Transl. Med., 7:287ra72, 2015.   (DOI: 10.1126/scitranslmed.3009986)
  • Szabo, N.E., da Silva, R.V., Sotocinal, S.G., Zeilhofer, H.U., Mogil, J.S., and Kania, A.  Hoxb8 intersection defines a role for Lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity and nociception.  J. Neurosci., 35:5233-5246, 2015.  (DOI: 10.1523/JNEUROSCI.4690-14.2015) ◊◊
  • Martin, L.J., Hathaway, G., Isbester, K., Mirali, S., Acland, E.L., Niederstrasser, N., Slepian, P.M., Trost, Z., Bartz, J.A., Sapolsky, R.M., Sternberg, W.F., Levitin, D.J., and Mogil, J.S.  Reducing social stress elicits emotional contagion of pain in mouse and human strangers.  Curr. Biol., 25:326-332, 2015.   (DOI: 10.1016/j.cub.2014.11.028) ††◊◊◊◊
  • Cahill, L.S., Laliberte, C.L., Liu, X.J., Bishop, J., Nieman, B.J., Mogil, J.S., Sorge, R.E., Jones, C.D., Salter, M.W., and Henkelman, R.M.  Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse.  Mol. Pain, 10:60, 2014.   (DOI: 10.1186/1744-8069-10-60)
  • Wieskopf, J.S., Pan, Y.-X., Marcovitz, J., Tuttle, A.H., Majumdar, S., Pidakala, J., Pasternak, G.W., and Mogil, J.S.  Broad spectrum analgesic efficacy of IBNtxA is mediated by exon 11-associated splice variants of the mu-opioid receptor gene.  Pain, 155:2063-2070, 2014.   (DOI:10.1016/j.pain.2014.07.014)
  • Tang, S., Ding, Y., Sibille, E. Mogil, J.S., Lariviere, W.R., and Tseng, G.C.  Imputation of truncated p-values for meta-analysis methods and its genomic application.  Ann. Appl. Stat., 8:2150-2174, 2014.   (DOI: 10.1214/14-AOAS747)
  • Sorge, R.E., Martin, L.J., Isbester, K.A., Sotocinal, S.G., Rosen, S., Tuttle, A.H., Wieskopf, J.S., Acland, E.L., Dokova, A., Kadoura, B., Leger, P., Mapplebeck, J.C.S., McPhail, M., Delaney, A., Wigerblad, G., Schumann, A.P., Quinn, T., Frasnelli, J., Svensson, C.I., Sternberg, W.F., and Mogil, J.S.  Olfactory exposure to males, including human males, stresses rodents.  Nat. Meth., 11:629-632, 2014.   (DOI:10.1038/nmeth.2935) ♥††††◊◊◊◊◊
  • Farmer, M.A., Leja, A., Foxen-Craft, E., Chan, L., MacIntyre, L.C., Niaki, T., Chen, M., Mapplebeck, J.C.S., Tabry, V., Topham, L., Sukosd, M., Binik, Y.M., Pfaus, J.G., and Mogil, J.S.  Pain reduces sexual motivation in female but not male mice.  J. Neurosci., 34:5747-5753, 2014.   (DOI:10.1523/JNEUROSCI.5337-13.2014) ◊◊◊
  • Kristiansen, F.L., Olesen, A.E., Brock, C., Gazerani, P., Petrini, L., Mogil, J.S., and Drewes, A.M.  The role of pain catastrophizing in experimental pain perception.  Pain Pract., 14:E136-E145, 2014.   (DOI: 10.1111/papr.12150)
  • Daou, I., Tuttle, A.H., Long, G., Wieskopf, J.S., Bonin, R., Ase, A., Wood, J.N., De Koninck, Y., Ribeiro-da-Silva, A., Mogil, J.S., and Seguela, P.  Remote optogenetic activation and sensitization of pain pathways in freely moving mice.  J. Neurosci., 33:18631-18640, 2013.   (DOI: 10.1523/JNEUROSCI.2424-13.2013) ††
  • Corder, G., Doolen, S., Donahue, R.R., Winter, M.K., Jutras, B.L., He, Y., Hu, X., Wieskopf, J.S., Mogil, J.S., Storm, D.R., Wang, Z.J., McCarson, K.E., and Taylor, B.K.  Constitutive m?opioid receptor activity leads to long-term endogenous analgesia and dependence.  Science, 341:1394-1399, 2013.   (DOI: 10.1126/science.1239403) †††◊◊
  • Belfer, I., Segall, S.K., Lariviere, W.R., Smith, S.B., Dai, F., Slade, G.G., Rashid, N.U., Mogil, J.S., Campbell, C.M., Edwards, R.R., Liu, Q., Bair, E., Maixner, W., and Diatchenko, L.  Pain modality- and sex-specific effects of COMT functional variants.  Pain, 154:1368-1376, 2013.   (DOI: 10.1016/j.pain.2013.04.028) ††
  • Chanda, M.L., Tuttle, A.H., Baran, I., Atlin, C., Guindi, D., Hathaway, G., Israelian, N., Levenstadt, J., Low, D., Macrae, L., O'Shea, L., Silver, A., Zendegui, E., Lenselink, A.M., Spijker, S., Ferrari, M.D., van den Maagdenberg, A.M.J.M., and Mogil, J.S.  Behavioral evidence for photophobia and stress-related ipsilateral head pain in transgenic Cacna1a mutant mice.  Pain, 154:1254-1262, 2013.  (DOI: 10.1016/j.pain.2013.03.038)
  • Melemedjian, O.K., Khoutorsky, A., Sorge, R.E., Yan, J., Asiedu, M.N., Valdez, A., Ghosh, S., Dussor, G., Mogil, J.S., Sonenberg, N., and Price, T.J.  mTORC1 inhibition induces pain via IRS1-dependent feedback activation of ERK.  Pain, 154:1080-1091, 2013.   (DOI: 10.1016/j.pain.2013.03.021)
  • Sorge, R.E., LaCroix-Fralish, M.L., Tuttle, A.H., Khoutorsky, A., Sotocinal, S.G., Austin, J.-S., Melmed, K., Labialle, S., Schmidt, J.V., Wood, J.N., Naumova, A.K., and Mogil, J.S.  The yin and yang of pain: variability in formalin test nociception and morphine analgesia produced by the Yin Yang 1 transcription factor gene.  Genes Brain Behav., 12:405-413, 2013. (DOI: 10.1111/gbb.12030)
  • Khoutorsky, A., Yanagiya, A., Gkogkas, C., Fabian, M.R., Prager-Khoutorsky, M., Cao, R., Gamache, K., Bouthiette, F., Parsyan, A., Sorge, R.E., Mogil, J.S., Nader, K., Lacaille, J.?C., and Sonenberg, N.  Control of synaptic plasticity and memory via suppression of poly(A)-binding protein.  Neuron, 78:298-311, 2013.   (DOI: 10.1016/j.neuron.2013.02.025)
  • Hastie, B.A., Riley, J.L., III, Kaplan, L., Herrera, D.G., Campbell, C.M., Virtusio, K., Mogil, J.S., Wallace, M.R., and Fillingim, R.B.  Ethnicity interacts with the OPRM1 gene in experimental pain sensitivity.  Pain, 153:1610-1619, 2012.  (DOI: 10.1016/j.pain.2012.03.022)
  • Tsao, D., Wieskopf, J.S., Rashid, N., Sorge, R.E., Redler, R.L., Segall, S.K., Mogil, J.S., Maixner, W., Dokholyan, N.V., and Diatchenko, L.  Serotonin-induced hypersensitivity via inhibition of catechol-O-methyltransferase activity.  Mol. Pain, 8:25, 2012.   (DOI: 10.1186/1744-8069-8-25)
  • Malfait, A.M., Seymour, A.B., Gao, F., Tortorella, M.D., Hellio Le Graverand-Gastineau, M.P., Wood, L.S., Doherty, M., Doherty, S., Zhang, W., Arden, N.K., Vaughn, F.L., Leaverton, P.E., Spector, T.D., Hart, D.J., Maciewicz, R.A., Muir, K.R., Das, R., Sorge, R.E., Sotocinal, S.G., Schorscher-Petcu, A., Valdes, A.M., and Mogil, J.S.  A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype.  Ann. Rheum. Dis., 71:1042-1048, 2012.  (DOI:10.1136/annrheumdis-2011-200300)
  • Sorge, R.E., Trang, T., Dorfman, R., Smith, S.B., Beggs, S., Ritchie, J., Austin, J.-S., Zaykin, D.V., Vander Meulen, H., Costigan, M., Herbert, T.A., Yarkoni-Abitbul, M., Tichauer, D., Livneh, J., Gershon, E., Zheng, M., Tan, K., John, S.L., Slade, G.D., Jordan, J., Woolf, C.J., Peltz, G., Maixner, W., Diatchenko, L., Seltzer, Z., Salter, M.W. and Mogil, J.S.  Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.  Nat. Med., 18:595-599, 2012.  (DOI:  10.1038/nm.2710) ††††◊◊◊
  • Shekarabi, M., Moldrich, R., Rasheed, S., Salin-Cantegrel, A., Laganiere, J., Rochefort, D., Hince, P., Huot, K., Gaudet, R., Kurniawan, N., Sotocinal, S.G., Ritchie, J., Dion, P., Mogil, J.S., Richards, L., and Rouleau, G.  Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum.  J. Neurosci., 32:3865-3876, 2012.  (DOI:  10.1523/JNEUROSCI.3679-11.2012) †
  • Matsumiya, L.C., Sorge, R.E., Sotocinal, S.G., Tabaka, J.M., Wieskopf, J.S., Zaloum, A., King, O.D., and Mogil, J.S.  Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice.  J. Am. Assoc. Lab. Anim. Sci., 51:42-49, 2012.   (PMID:  22330867) †††◊
  • Sorge, R.E., LaCroix-Fralish, M.L., Tuttle, A.H., Sotocinal, S.G., Austin, J.-S., Ritchie, J., Chanda, M.L., Graham, A.C., Topham, L., Beggs, S., Salter, M.W., and Mogil, J.S.  Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice.  J. Neurosci., 31:15450-15454, 2011.  (DOI:10.1523/JNEUROSCI.3859-11.2011) ††††◊
  • Mogil, J.S., Sorge, R.E., LaCroix-Fralish, M.L., Smith, S.B., Fortin, A., Sotocinal, S.G., Ritchie, J., Austin, J.-S., Schorscher-Petcu, A., Melmed, K., Czerminski, J., Bittong, R.A., Mokris, J.B., Neubert, J.K., Campbell, C.M., Edwards, R.R., Campbell, J.N., Crawley, J.N., Lariviere, W.R., Wallace, M.R., Sternberg, W.F., Balaban, C.D., Belfer, I., and Fillingim, R.B.  Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction.  Nat. Neurosci., 14:1569-1573, 2011.  (DOI: 10.1038/nn.2941) ††◊
  • Farmer, M.A., Taylor, A.M., Bailey, A.L., Tuttle, A.H., MacIntyre, L.C., Milagrosa, Z.E., Crissman, H.P., Bennett, G.J., Ribeiro-da-Silva, A., Binik, Y.M., and Mogil, J.S.  Repeated vulvovaginal fungal infections cause persistent pain in a mouse model of vulvodynia.  Sci. Transl. Med., 3:101ra91, 2011.  (DOI: 10.1126/scitranslmed.3002613) ††
  • Sotocinal, S.G., Sorge, R.E., Zaloum, A., Tuttle, A.H., Martin, L.J., Wieskopf, J.S., Mapplebeck, J.C.S., Wei, P., Zhan, S., Zhang, S., McDougall, J.J., King, O.D., and Mogil, J.S.  The Rat Grimace Scale: a partially automated method for quantifying pain in the laboratory rat via facial expressions.  Mol. Pain, 7:55, 2011.  (DOI: 10.1186/1744-8069-7-55) ††††◊◊◊◊
  • Langford, D.J., Tuttle, A.H., Briscoe, C., Harvey-Lewis, C., Baran, I., Gleeson, P.,  Fischer, D.B., Buonora, M., Sternberg, W.F., and Mogil, J.S.  Varying perceived social threat modulates pain behavior in male mice.  J. Pain, 12:125-132, 2011.  (DOI: 10.1016/j.jpain.2010.06.003)
  • Fortin, A., Diez, E., Ritchie, J., Sotocinal, S.G., Dube, M.-P., Gagne, M., Paquette, O., Skamene, E., and Mogil, J.S.  Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1 (tyrosinase-related protein 1).  Genes Brain Behav., 9:856-867, 2010.  (DOI: 10.1111/j.1601-183X.2010.00618.x)
  • Schorscher-Petcu, A., Sotocinal, S.G., Ciura, S., Dupre, A., Ritchie, J., Sorge, R.E., Crawley, J.N., Hu, S.-B., Nishimori, K., Young, L.J., Tribollet, E., Quirion, R., and Mogil, J.S.  Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse.  J. Neurosci., 30:8274-8284, 2010.   (DOI: 10.1126/scitranslmed.3002613)
  • Mogil, J.S., Graham, A.C., Ritchie, J., Hughes, S.F., Austin, J.-S., Schorscher-Petcu, A., Langford, D.J., and Bennett, G.J.  Hypolocomotion, asymmetrically directed behaviors (licking, lifting, flinching, and shaking) and dynamic weight bearing (gait) changes are not measures of neuropathic pain in mice.  Mol. Pain, 6:34, 2010.  (DOI: 10.1186/1744-8069-6-34) ††
  • Langford, D.J., Bailey, A.L., Chanda, M.L., Clarke, S.E., Drummond, T.E., Echols, S., Glick, S., Ingrao, J., Klassen-Ross, T., LaCroix-Fralish, M.L., Matsumiya, L., Sorge, R.E., Sotocinal, S.G., Tabaka, J.M., Wong, D., van den Maagdenberg, A.M.J.M., Ferrari, M.D., Craig, K.D., and Mogil, J.S.  Coding of facial expressions of pain in the laboratory mouse.  Nat. Meth., 7:447-449, 2010.  (DOI: 10.1038/NMETH.1455) ♥†††††◊◊◊◊
  • Malfait, A.-M., Ritchie, J., Gil, A.S., Austin, J.-S., Hartke, J., Qin, W., Tortorella, M.D.,  and Mogil, J.S.  ADAMTS-5 deficient mice do not develop mechanical allodynia associated with osteoarthritis following medial meniscal destabilization.  Osteoarthritis Cartilage, 18:572-580, 2010.  (DOI: 10.1016/j.joca.2009.11.013) ††
  • Li, X., Sahbaie, P., Zheng, M., Ritchie, J., Peltz, G., Mogil, J.S., and Clark, J.D.  Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors.  Mol. Pain, 6:11, 2010.  (DOI: 10.1186/1744-8069-6-11)
  • Langford, D.J., Tuttle, A.H., Brown, K., Deschenes, S., Fischer, D.B., Mutso, A., Root, K.C., Sotocinal, S.G., Stern, M.A., Mogil, J.S., and Sternberg, W.F.  Social approach to pain in laboratory mice.  Social Neurosci., 5:163-170, 2010.  (DOI: 10.1080/17470910903216609) ††◊
  • Juni, A., Cai, M., Stankova, M., Waxman, A.R., Arout, C., Klein, G., Dahan, A., Hruby, V.J., Mogil, J.S., and Kest, B.  Sex-specific mediation of opioid-induced hyperalgesia by the melanocortin-1 receptor.  Anesthesiology, 112:181-188, 2010.  (DOI: 10.1097/ALN.0b013e3181c53849)
  • Schorscher-Petcu, A., Austin, J.-S., Mogil, J.S., and Quirion, R.  Role of central calcitonin gene-related peptide (CGRP) in locomotor, anxiety- and depression-like behaviors in two mouse strains exhibiting a CGRP-dependent difference in thermal pain sensitivity.  J. Mol. Neurosci., 39:125-136, 2009.  (DOI: 10.1097/ALN.0b013e3181c53849)
  • Kest, B., Smith, S.B., Schorscher-Petcu, A., Austin, J.-S., Ritchie, J., Klein, G., Rossi, G.C., Fortin, A. and Mogil, J.S.  Gnao1 (Gao protein) is a likely genetic contributor to variation in physical dependence on opioids in mice.  Neuroscience, 162:1255-1264, 2009.   (DOI: 10.1016/j.neuroscience.2009.05.027)
  • LaCroix-Fralish, M.L., Mo, G., Smith, S.B., Sotocinal, S.G., Ritchie, J., Austin, J.-S., Melmed, K., Schorscher-Petcu, A., Laferriere, A.C., Lee, T.H., Romanovsky, D., Liao, G., Behlke, M.A., Clark, D.J., Peltz, G., Seguela, P., Dobretsov, M., and Mogil, J.S.  The b3 subunit of the Na+,K+-ATPase mediates variable nociceptive sensitivity in the formalin test.  Pain, 144:294-302, 2009.  (DOI: 10.1016/j.pain.2009.04.028)
  • Loggia, M.L., Bushnell, M.C., Tetreault, M., Thiffault, I., Bherer, C., Mohammed, N.K., Kuchinad, A.A., Laferriere, A., Dicaire, M.-J., Loisel, L., Mogil, J.S., and Brais, B.  Carriers of recessive WKN/HSN2 mutations for hereditary sensory and autonomic neuropathy type 2 (HSAN2) are more sensitive to thermal stimuli.  J. Neurosci., 29:2162?2166, 2009.  (DOI: 10.1523/?JNEUROSCI.4633-08.2009)
  • Loggia, M.L., Mogil, J.S., and Bushnell, M.C.  Experimentally induced mood changes preferentially affect pain unpleasantness.  J. Pain, 9:784-791, 2008.   (DOI: 10.1016/j.jpain.2008.03.014) ††
  • Smith, S.B., Marker, C.L., Perry, C., Liao, G., Sotocinal, S.G., Austin, J.-S., Melmed, K., Clark, D.J., Peltz, G., Wickman, K., and Mogil, J.S.  Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes.  Pharmacogenet. Genom., 18:231?242, 2008.   (DOI: 10.1097/FPC.0b013e3282f55ab2)
  • Callahan, B.L., Gil, A.S.C., Levesque, A., and Mogil, J.S.  Modulation of mechanical and thermal nociceptive sensitivity in the laboratory mouse by behavioral state.  J. Pain, 9:174?184, 2008.  (DOI: 10.1016/j.jpain.2007.10.011) ††
  • Zhang, J., Shi, X.Q., Echeverry, S., Mogil, J.S., De Koninck, Y. and Rivest, S.   Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain.  J. Neurosci., 27:12396-12406, 2007.   (DOI: 10.1523/JNEUROSCI.3016-07.2007) ††††
  • Mogil, J.S., Ritchie, J., Sotocinal, S.G., Smith, S.B., Croteau, S., Levitin, D.J., and Naumova, A.K.  Screening for pain phenotypes: analysis of three congenic mouse strains on a battery of nine nociceptive assays.  Pain, 126:24-34, 2006.  (DOI: 10.1016/j.pain.2006.06.004) ††
  • Green, A.D., Young, K.K., Lehto, S.G., Smith, S.B., and Mogil, J.S.  Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse.  Pain, 124:50-58, 2006.  (DOI: 10.1016/j.pain.2006.03.023) ††
  • Chanda, M.L. and Mogil, J.S.  Sex differences in the effects of amiloride on formalin test nociception in mice.  Am. J. Physiol. Regul. Integr. Comp. Physiol., 291:R335-342, 2006.  (DOI: 10.1152/ajpregu.00902.2005)
  • Langford, D.J., Crager, S.E., Shehzad, Z., Smith, S.B., Sotocinal, S.G., Levenstadt, J.S., Chanda, M.L., Levitin, D.J., and Mogil, J.S.  Social modulation of pain as evidence for empathy in mice.  Science, 312:1967-1970, 2006.  (DOI: 10.1126/science.1128322) ††††◊◊◊
  • Mogil, J.S., Breese, N.M., Witty, M.-F., Ritchie, J., Rainville, M.-L., Ase, A., Abbadi, N., Stucky, C.L., and Seguela, P.  Transgenic expression of a dominant?negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli.  J. Neurosci., 25:9893-9901, 2005.  (DOI: 10.1523/JNEUROSCI.2019-05.2005) ††
  • Mogil, J.S., Smith, S.B., O’Reilly, M.K., and Plourde, G.  Influence of nociception and stress-induced antinociception on genetic variation in isoflurane anesthetic potency among mouse strains.  Anesthesiology, 103:751-758, 2005.   (DOI: 10.1097/00000542-200510000-00013)
  • Mogil, J.S., Miermeister, F., Seifert, F., Strasburg, K., Zimmermann, K., Reinold, H., Austin, J.-S., Bernardini, N., Chesler, E.J., Hofmann, H.A., Hordo, C., Messlinger, K., Nemmani, K.V.S., Rankin, A.L., Ritchie, J., Siegling, A., Smith, S.B., Sotocinal, S.G., Vater, A., Lehto, S.G., Klussmann, S., Quirion, R., Michaelis, M., Devor, M., and Reeh, P.W.  Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene.  Proc. Natl. Acad. Sci., U.S.A., 102:12938-12943, 2005.   (DOI: 10.1073/pnas.0503264102) †††
  • LaCroix-Fralish, M.L., Rutkowski, M.D., Weinstein, J.N., Mogil, J.S., and DeLeo, J.A.  The magnitude of mechanical allodynia in a rodent model of lumbar radiculopathy is dependent on strain and sex.  Spine, 30:1821-1827, 2005.   (DOI: 10.1097/01.brs.0000174122.63291.38)
  • Mogil, J.S., Ritchie, J., Smith, S.B., Strasburg, K., Kaplan, L., Wallace, M.R., Romberg, R.R., Bijl, H., Sarton, E.Y., Fillingim, R.B., and Dahan, A.  Melanocortin-1 receptor gene variants affect pain and m-opioid analgesia in mice and humans.  J. Med. Genet., 42:583?587, 2005.  (DOI: 10.1136/jmg.2004.027698) †††◊
  • Nemmani, K.V.S., Lalonde, J., and Mogil, J.S.  Region-specific changes of CaMKIV in the mouse brain following chronic morphine treatment.  Neuroreport, 16:879-882, 2005.   (DOI: 10.1097/00001756-200506210-00001)
  • Fillingim, R.B., Kaplan, L., Staud, R., Ness, T.J., Glover, T.L., Campbell, C.M., Mogil, J.S., and Wallace, M.R.  The A118G single nucleotide polymorphism of the m-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans.  J. Pain, 6:159-167, 2005.  (DOI: 10.1016/j.jpain.2004.11.008) ††††
  • Sternberg, W.F., Chesler, E.J., Wilson, S.G., and Mogil, J.S.  Acute progesterone can recruit sex-specific neurochemical mechanisms mediating swim stress-induced and kappa?opioid analgesia in mice.  Horm. Behav., 46:467-473, 2004.   (DOI: 10.1016/j.yhbeh.2004.05.007)
  • Kest, B., Palmese, C.A., Juni, A., Chesler, E.J., and Mogil, J.S.  Mapping of a quantitative trait locus for morphine withdrawal severity.  Mamm. Genome, 15:610?617, 2004.   (DOI: 10.1007/s00335-004-2367-3)
  • Sternberg, W.F., Ritchie, J., and Mogil, J.S.  Qualitative sex differences in k-opioid analgesia in mice are dependent on age.  Neurosci. Lett., 363:178-181, 2004.   (DOI: 10.1016/j.neulet.2004.04.004)
  • Nemmani, K.V.S., Grisel, J.E., Stowe, J.R., Smith-Carliss, R., and Mogil, J.S.  Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time.  Pain, 109:274-283, 2004.   (DOI: 10.1016/j.pain.2004.01.035) ††
  • Smith, S.B., Crager, S.E., and Mogil, J.S.  Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains.  Life Sci., 74:2593?2604, 2004.   (DOI: 10.1016/j.lfs.2004.01.002) †† 
  • Chesler, E.J., Ritchie, J., Kokayeff, A., Lariviere, W.R., Wilson, S.G., and Mogil, J.S.  Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited.  Pain, 106:325-335, 2003.  (DOI: 10.1016/S0304-3959(03)00330-0) ††
  • Bon, K., Lichtensteiger, C.A., Wilson, S.G., and Mogil, J.  Characterization of cyclophosphamide cystitis, a model of visceral and referred pain, in the mouse: species and strain differences.  J. Urol., 170:1008-1012, 2003.  (DOI: 10.1097/01.ju.0000079766.49550.94) ††
  • Wilson, S.G., Bryant, C.D., Lariviere, W.R., Olsen, M.S., Giles, B.E., Chesler, E.J., and Mogil, J.S.  The heritability of antinociception II:  pharmacogenetic mediation of three over-the-counter analgesics in mice.  J. Pharmacol. Exp. Ther., 305:755?764, 2003.   (DOI: 10.1124/jpet.102.047902)
  • Mogil, J.S., Wilson, S.G., Chesler, E.J., Rankin, A.J., Nemmani, K.V.S., Lariviere, W.R., Groce, M.K., Wallace, M.R., Kaplan, L., Staud, R., Ness, T.J., Glover, T.L., Stankova, M., Mayorov, A., Hruby, V.J., Grisel, J.E., and Fillingim, R.B.  The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans.  Proc. Natl. Acad. Sci. USA, 100:4867-4872, 2003.  (DOI: 10.1073/pnas.0730053100) ††††◊
  • Nemmani, K.V.S. and Mogil, J.S.  Serotonin-GABA interactions in the modulation of mu? and kappa-opioid analgesia.  Neuropharmacology, 44:304-310, 2003.   (DOI: 10.1016/S0028-3908(02)00374-X)
  • Wilson, S.G., Smith, S.B., Chesler, E.J., Melton, K.A., Haas, J.J., Mitton, B., Strasburg, K., Hubert, L., Rodriguez-Zas, S.L., and Mogil, J.S.  The heritability of antinociception: common pharmacogenetic mediation of five neurochemically distinct analgesics.  J. Pharmacol. Exp. Ther., 304:547-559, 2003.  (DOI: 10.1124/jpet.102.041889) ††
  • Chesler, E.J., Wilson, S.G., Lariviere, W.R., Rodriguez-Zas, S.L., and Mogil, J.S.  Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive.  Neurosci. Biobehav. Rev., 26:907-923, 2002.  (DOI: 10.1016/S0149-7634(02)00103-3) ††††
  • Kest, B., Palmese, C.A., Hopkins, E., Adler, M., Juni, A., and Mogil, J.S.  Naloxone?precipitated withdrawal jumping in 11 inbred mouse strains: evidence for common genetic mechanisms in acute and chronic morphine physical dependence.  Neuroscience, 115:463-469, 2002.  (DOI: 10.1016/S0306-4522(02)00458-X) ††
  • Chesler, E.J., Wilson, S.G., Lariviere, W.R., Rodriguez-Zas, S.L., and Mogil, J.S. Influences of laboratory environment on behavior.  Nat. Neurosci., 5:1101-1102, 2002.   (DOI: 10.1038/nn1102-1101) †††
  • Kest, B., Hopkins, E., Palmese, C.A., Adler, M., and Mogil, J.S.  Genetic variation in morphine analgesic tolerance: a survey of 11 inbred mouse strains.  Pharmacol. Biochem. Behav., 73:821-828, 2002.  (DOI: 10.1016/S0091-3057(02)00908-5) ††
  • Bon, K., Wilson, S.G., Mogil, J.S., and Roberts, W.J.  Genetic evidence for the correlation of deep dorsal horn Fos protein immunoreactivity with tonic formalin pain behavior.  J. Pain, 3: 181-189, 2002.  (DOI: 10.1054/jpai.2002.123710)
  • Lariviere, W.R., Wilson, S.G., Laughlin, T.M., Kokayeff, A., West, E.E., Adhikari, S.M., Wan, Y., and Mogil, J.S.  Heritability of nociception.  III. Genetic relationships among commonly used assays of nociception and hypersensitivity.  Pain, 97: 75-86, 2002.   (DOI: 10.1016/S0304-3959(01)00492-4) †††
  • Wilson, S.G., Chesler, E.J., Hain, H., Rankin, A.J., Schwarz, J.Z., Call, S.B., Murray, M.R., West, E.E., Teuscher, C., Rodriguez-Zas, S., Belknap, J.K., and Mogil, J.S.  Identification of quantitative trait loci for chemical/inflammatory nociception in mice.  Pain, 96: 385-391, 2002.  (DOI: 10.1016/S0304-3959(01)00489-4)
  • Rizzi, A., Marzola, G., Bigoni, R., Guerrini, R., Salvadori, S.,Mogil, J.S., Regoli, D., and Calo', G.  Endogenous nociceptin signaling and stress-induced analgesia.  Neuroreport, 12: 3009-3013, 2001.  (DOI: 10.1097/00001756-200110080-00006)
  • Bergeson, S.E., Helms, M.L., O'Toole, L.A., Jarvis, M.W., Hain, H.S., Mogil, J.S. and Belknap, J.K.  Quantitative trait loci influencing morphine antinociception in four mapping populations.  Mamm. Genome, 12: 546-553, 2001.  (DOI: 10.1007/s003350020022) ††
  • Kest, B., Hopkins, E., Palmese, C.A., Chen, Z.-P., Mogil, J.S., and Pintar, J.E.  Morphine tolerance and dependence in nociceptin/orphanin FQ transgenic knock?out mice.  Neuroscience, 104: 217-222, 2001.  (DOI: 10.1016/S0306-4522(01)00037-9)
  • Wan, Y., Wilson, S.G., Han, J.S., and Mogil, J.S.  The effect of genotype on sensitivity to electroacupuncture analgesia.  Pain, 91: 5-13, 2001.   (DOI: 10.1016/S0304-3959(00)00416-4)
  • Mogil, J.S., Grisel, J.E., Bales, J.R., Hayward, M.D., Rubinstein, M., Belknap, J.K.,and Low, M.  Disparate spinal and supraspinal opioid antinociceptive responses in b?endorphin-deficient mutant mice.  Neuroscience, 101: 709-717, 2000.  (DOI: 10.1016/S0306-4522(00)00422-X)
  • Mogil, J.S., Chesler, E.J., Wilson, S.G., Juraska, J.M., and Sternberg, W.F.  Sex differences in thermal nociception and morphine antinociception in the rodent depend on genotype, Neurosci. Biobehav. Rev., 24: 375-389, 2000.  (DOI: 10.1016/S0149-7634(00)00015-4) ††
  • Hain, H., Belknap, J.K., and Mogil, J.S.  Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity.  J. Pharmacol. Exp. Ther., 291: 444-449, 1999.   (PMID: 10525057) †
  • Flores, C.M, Wilson, S.G., and Mogil, J.S.  Pharmacogenetic variability in neuronalnicotinic receptor-mediated antinociception.  Pharmacogenetics, 9: 619-625, 1999.   (DOI: 10.1097/00008571-199910000-00008)
  • Grisel, J.E., Mogil, J.S., Grahame, N.J., Rubinstein, M., Belknap, J.K., Crabbe, J.C., and Low, M.  Ethanol oral self-administration is increased in mutant mice with decreased b?endorphin expression.  Brain Res., 835: 62-67, 1999.   (DOI: 10.1016/S0006-8993(99)01384-0) ††
  • Kest, B., Wilson, S.G., and Mogil, J.S.  Sex differences in supraspinal morphine analgesia are dependent on genotype.  J. Pharmacol. Exp. Ther., 289: 1370-1375, 1999.  (PMID: 10336528) †††
  • Martìnez, V., Thakur, S., Mogil, J.S., Tachë, Y., and Mayer, E.A.  Differential effects of chemical and mechanical colonic irritation on behavioral pain response to intraperitoneal acetic acid in mice.  Pain, 81: 179-186, 1999.  (DOI: 10.1016/S0304-3959(99)00008-1) ††
  • Mogil, J.S., Wilson, S.G., Bon, K., Lee, S.E., Chung, K., Raber, P., Pieper, J.O., Hain, H.S., Belknap, J.K., Hubert, L., Elmer, G.I., Chung, J.M., and Devor, M.  Heritability of nociception.  II. 'Types' of nociception revealed by genetic correlation analysis.  Pain, 80: 83-93, 1999.  (DOI: 10.1016/S0304-3959(98)00196-1) †††
  • Mogil, J.S., Wilson, S.G., Bon, K., Lee, S.E., Chung, K., Raber, P., Pieper, J.O., Hain, H.S., Belknap, J.K., Hubert, L., Elmer, G.I., Chung, J.M., and Devor, M.  Heritability ofnociception.  I. Responses of eleven inbred mouse strains on twelve measures of nociception.  Pain, 80: 67-82, 1999.  (DOI: 10.1016/S0304-3959(98)00197-3) ††††
  • Mogil, J.S., Nessim, L.A., and Wilson, S.G.  Strain-dependent effects of supraspinal orphanin FQ/nociceptin on thermal nociceptive sensitivity in mice.  Neurosci. Lett., 261: 147-150, 1999.  (DOI: 10.1016/S0304-3940(99)00012-9)
  • Kest, B., Jenab, S., Brodsky, M., Sadowski, B., Belknap, J.K., Mogil, J.S., and Inturrisi, C.E.  Mu and delta opioid receptor analgesia, binding density, and mRNA levels in mice selectively bred for high and low analgesia.  Brain Res., 816: 381?389, 1999.   (DOI: 10.1016/S0006-8993(98)01141-X)
  • Kest, B., McLemore, G.L., Sadowski, B., Mogil, J.S., Belknap, J.K., and Inturrisi, C.E.  Acute morphine dependence in mice selectively-bred for high and low analgesia.  Neurosci. Lett., 256: 120-122, 1998.  (DOI: 10.1016/S0304-3940(98)00772-1)
  • Kest, B., Beckzowska, I., Franklin, S.O., Lee, C.E., Mogil, J.S., and Inturrisi, C.E.  Differences in delta opioid receptor antinociception, binding, and mRNA levels between BALB/c and CXBK mice.  Brain Res., 805: 131-137, 1998.   (DOI: 10.1016/S0006-8993(98)00696-9)
  • Grisel, J.E., Farrier, D.E., Wilson, S.G., and Mogil, J.S.  [Phe1Y(CH2-NH)Gly2] nociception?(1-13)-NH2 acts as an agonist of the orphanin FQ/nociceptin receptor in vivoEur. J. Pharmacol., 357: R1-R3, 1998.  (DOI: 10.1016/S0014-2999(98)00567-6)
  • Mogil, J.S., Lichtensteiger, C.A., and Wilson, S.G.  The effect of genotype on sensitivity to inflammatory nociception: characterization of resistant (A/J) and sensitive (C57BL/6J) inbred mouse strains.  Pain, 76: 115-125, 1998.  (DOI: 10.1016/S0304-3959(98)00032-3)
  • Mogil, J.S., Shin, Y.-H., McCleskey, E.W., Kim, S.-C., and Nah, S.-Y.  Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice.  Brain Res., 792: 218?228, 1998.  (DOI: 10.1016/S0006-8993(98)00133-4) ††
  • Sufka, K.J., Watson, G.S., Nothdurft, R.E., and Mogil, J.S.  Scoring the mouse formalin test: validation study.  Eur. J. Pain, 2: 351-358, 1998.  (DOI: 10.1016/S1090-3801(98)90033-7)
  • Mogil, J.S. and Wilson, S.G.  Nociceptive and morphine antinociceptive sensitivity of 129 and C57BL/6 inbred mouse strains: implications for transgenic knock-out studies.  Eur. J. Pain, 1: 293-297, 1997.  (DOI: 10.1016/S1090-3801(97)90038-0)
  • Mogil, J.S., Richards, S.P., O'Toole, L.A., Mitchell, S.R., Helms, M.L., Kest, B., and Belknap, J.K.  Identification of sex-specific quantitative trait loci mediating non-opioid swim stress-induced analgesia in female mice.  J. Neurosci., 17: 7995?8002, 1997.  (DOI:  10.1523/JNEUROSCI.17-20-07995.1997) ††
  • Mogil, J.S., Richards, S.P., O'Toole, L.A., Helms, M.L., Mitchell, S.R., and Belknap, J.K.  Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by d2-opioid receptors.  Pain, 70: 267-277, 1997.   (DOI: 10.1016/S0304-3959(97)03333-2) †††
  • Tian, J.-H., Xu, W., Fang, Y., Mogil, J.S., Grisel, J.E., Grandy, D.K., and Han, J.-S.  Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat.  Br. J. Pharmacol., 120: 676-680, 1997.  (DOI: 10.1038/sj.bjp.0700942) ††††
  • Kest, B., Lee, C.E., Mogil, J.S., and Inturrisi, C.E.  Blockade of morphine supersensitivity by an antisense oligodeoxynucleotide targeting the delta opioid receptor (DOR-1).  Life Sci., 60: PL155-159, 1997.  (DOI: 10.1016/S0024-3205(96)00704-7)
  • Tian, J.-H., Xu, W., Fang, Y., Grisel, J.E., Mogil, J.S., Grandy, D.K., and Han, J.-S.  Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia.  Neuroreport, 8: 497-500, 1997.  (DOI: 10.1097/00001756-199701200-00024) ††
  • Mogil, J.S. and Belknap, J.K.  Sex and genotype determine the selective activation of neurochemically-distinct forms of swim stress-induced analgesia.  Pharmacol. Biochem. Behav., 56: 61-66, 1997.  (DOI: 10.1016/S0091-3057(96)00157-8) ††
  • Mogil, J.S., Grisel, J.E., Reinscheid, R.K., Civelli, O., Belknap, J.K., and Grandy, D.K.  Orphanin FQ is a functional anti-opioid peptide.  Neuroscience, 75: 333-337, 1996.   (DOI: 10.1097/00001756-199609020-00012) ††††
  • Grisel, J.E., Mogil, J.S., Belknap, J.K., and Grandy, D.K.  Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide.  Neuroreport, 7: 2125-2129, 1996.   (DOI: 10.1097/00001756-199609020-00012) †††
  • Mogil, J.S., Grisel, J.E., Zhang, G., Belknap, J.K., and Grandy, D.K.  Functional antagonism of m-, δ- and κ-opioid antinociception by orphanin FQ.  Neurosci. Lett., 214: 131-134, 1996.  (DOI: 10.1016/0304-3940(96)12917-7) †††
  • Rubinstein, M.*, Mogil, J.S.*, Japón, M., Chan, E.C., Allen, R.G., and Low, M.J.  Absence of opioid stress-induced analgesia in mice lacking b-endorphin by site-directed mutagenesis.  Proc. Natl. Acad. Sci., USA, 93: 3995-4000, 1996.  (*co-first authors)  (DOI: 10.1073/pnas.93.9.3995) ††††
  • Mogil, J.S., Kest, B., Sadowski, B., and Belknap, J.K.  Differential genetic mediation of sensitivity to morphine in genetic models of opiate sensitivity: influence of nociceptive assay.  J. Pharmacol. Exp. Ther., 276: 532-544, 1996.  (PMID:  8632319) †††
  • Mogil, J.S., Sternberg, W.F., Balian, H., Liebeskind, J.C., and Sadowski, B.  Opioid and non?opioid swim stress-induced analgesia: a parametric analysis in mice.  Physiol. Behav., 59: 123-132, 1996.  (DOI: 10.1016/0031-9384(95)02073-X) †††
  • Kest, B., Brodsky, M., Sadowski, B., Mogil, J.S., and Inturrisi, C.E.  Mu-opiate receptor (Mor-1) mRNA levels are altered in mice with differential analgesic sensitivity to the mu agonist, DAMGO.  Analgesia, 1: 498-501, 1995.  (not MEDLINE indexed)
  • Sternberg, W.F., Mogil, J.S., Kest, B., Page, G.G., Leong, Y., Yam, V., and Liebeskind, J.C.  Neonatal testosterone exposure influences neurochemistry of swim stress-induced analgesia in adult mice.  Pain, 63: 321-326, 1995.  (DOI: 10.1016/0304-3959(95)00059-3) ††
  • Mogil, J.S., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines.  Behav. Genet., 25: 397-406, 1995.  (DOI: 10.1007/BF02197290)
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C.  1,3-di-o-tolylguanidine (DTG) differentially affects acute and tonic formalin pain: antagonism by rimcazole.  Pharmacol. Biochem. Behav., 52: 175-178, 1995.   (DOI: 10.1016/0091-3057(95)00085-B)
  • Vaccarino, F.J., Mogil, J.S., and Stinus, L.  Chronic dopamine antagonism facilitates opiate?induced feeding.  J. Psychiat. Neurosci., 20: 210-214, 1995.  (PMID:  7786882) 
  • Belknap, J.K., Mogil, J.S., Helms, M.L., O'Toole, L.A., Richards, S.P., and Bergeson, S.E.  Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/6 and DBA/2 mouse strains.  Life Sci., 57: PL117-124, 1995.   (DOI:  10.1016/0024-3205(95)02040-P) ††
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C.  Antinociception following 1,3-di-o-tolylguanidine (DTG), a selective sigma receptor ligand.  Pharmacol. Biochem. Behav., 50: 587-592, 1995.   (DOI: 10.1016/0091-3057(94)00346-7)
  • Mogil, J.S., Marek, P., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., and Liebeskind, J.C.  One or two genetic loci mediate high opiate analgesia in selectively bred mice.  Pain, 60: 125-135, 1995.  (DOI: 10.1016/0304-3959(94)00098-Y)
  • Mogil, J.S., Marek, P., O'Toole, L.A., Helms, M.L., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia.  Brain Res., 653: 16-22, 1994.   (DOI: 10.1016/0006-8993(94)90366-2) ††
  • Mogil, J.S., Sternberg, W.F., Kest, B., Marek, P., and Liebeskind, J.C.  Sex differences in the antagonism of swim stress-induced analgesia: effects of gonadectomy and estrogen replacement.  Pain, 253: 17-25, 1993.  (DOI: 10.1016/0304-3959(93)90050-Y) ††††
  • Marek, P., Mogil, J.S., Belknap, J.K., Sadowski, B., and Liebeskind, J.C.  Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalties.  Brain Res., 608: 353-357, 1993.  (DOI: 10.1016/0006-8993(93)91479-C)
  • Mogil, J.S., Marek, P., Yirmiya, R., Balian, H., Sadowski, B., Taylor, A.N., and Liebeskind, J.C.  Antagonism of the non-opioid component of ethanol-induced analgesia by the NMDA receptor antagonist MK-801.  Brain Res., 602: 126-130, 1993.   (DOI: 10.1016/0006-8993(93)90251-H)
  • Marek, P., Mogil, J.S., Sternberg, W.F., Panocka, I., and Liebeskind, J.C.  N?Methyl-D-aspartic acid (NMDA) receptor antagonist MK-801 blocks non-opioid stress-induced analgesia.  II. Studies using three different water temperature paradigms and selectively bred mice.  Brain Res., 578: 197-203, 1992.  (DOI: 10.1016/0006-8993(92)90248-8) ††
  • Ben-Eliyahu, S., Marek, P., Vaccarino, A.L., Mogil, J.S., Sternberg, W.F., and Liebeskind, J.C.  The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat.  Brain Res., 575: 304-308, 1992.  (DOI: 10.1016/0006-8993(92)90094-P) †††

Please provide your name, e-mail address as well as the name and e-mail address of the intended recipient in the spaces provided below:

Your Full Name:
Your Email:
Recipient's Full Name:
Recipient's Email:
Comments:
Department of Psychology 
McGill University 
1205 Dr. Penfield Avenue, Rm. N7/42
Montreal, QC  H3A 1B1

Canada  

jeffrey.mogil@mcgill.ca
Tel.  514.398.6085
Fax.  514.398.4896
Lab.  514.398.2742
The Pain Genetics Lab is committed to maintaining our users' privacy on the internet. Any information gathered on this website will be used only for the purposes for which it was collected. In the case of any information gathered without the direct knowledge of the user, such information will not be used to identify the user. The Pain Genetics Lab will never share any information gathered with third parties except in cases where it is reasonable to assume implicit agreement or explicit consent has been given.