Original Papers

Clarivate Highly Cited Paper (top 1% of field for its age):  ♥

Clarivate Web of Science citations to date:  †20+, ††50+, †††100+, ††††200+, †††††500+

Altmetric score:  ◊20+, ◊◊50+, ◊◊◊100+, ◊◊◊◊200+, ◊◊◊◊◊500+


  • Lister, K.C., Maldonado Bouchard, S., Markova, T., Aternali, A., Denecli, P., Donayre Pimentel, S., Majeed, M., Austin, J.-S., Williams, A.C.deC., and Mogil, J.S.  Chronic pain produces hypervigilance to predator odor in mice.  Curr. Biol., 30:R866-R867, 2020.   (DOI:  10.1016/j.cub.2020.06.025) ◊

  • Muralidharan, A., Sotocinal, S.G., Austin, J.-S., and Mogil, J.S.  The influence of aging and duration of injury on the anti-allodynic efficacy of analgesics in laboratory mice.  Pain Rep., 5:e824, 2020.  (DOI: 10.1097/PR9.0000000000000824)
  • Linnstaedt, S.D., Rueckeis, C.A., Riker, K.D., Pan, Y., Wu, A., Yu, S., Wanstrath, B., Gonzalez, M., Harmon, E., Green, P., Chen, C., King, T., Lewandowski, C., Hendry, P.L., Pearson, C., Kurz, M.C., Datner, E., Velilla, M.A., Domeier, R., Liberzon, I., Mogil, J.S., Levine, J., and McLean, S.A.  microRNA-19b predicts widespread pain and posttraumatic stress symptom risk in a sex-dependent manner following trauma exposure.  Pain, 161:47?60, 2020.   (DOI:  10.1097/j.pain.0000000000001709)
  • Petitjean, H., Bourojeni, F.B., Tsao, D., Davidova, A., Sotocinal, S.G., Mogil, J.S., Kania, A., and Sharif-Naeini, R.  Recruitment of spinoparabrachial neurons by dorsal horn calretinin neurons.  Cell Rep., 28:1429-1438, 2019.   (DOI:  10.1016/j.celrep.2019.07.048)
  • Parisien, M., Samoshkin, A., Tansley, S.N., Piltonen, M.H., Martin, L.J., El-Hachem, N., Dagostino, C., Allegri, M., Mogil, J.S., Khoutorsky, A., and Diatchenko, L.  Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain.  Pain, 160:932-944, 2019.   (DOI:  10.1097/j.pain.0000000000001471)
  • Tansley, S.N., Macintyre, L.C., Diamond, L., Sotocinal, S.G., George, N., Meluban, L., Austin, J.-S., Coderre, T.J., Martin, L.J., and Mogil, J.S.  Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity.  Pain, 160:784-792, 2019.  (DOI:  10.1097/j.pain.0000000000001454)
  • Smith, S.B., Parisien, M., Bair, E., Belfer, I., Chabot-Dore, A.-J., Gris, P., Khoury, S. Tansley, S., Torosyan, Y., Zaykin, D.V., Bernhardt, O., de Oliveira Serrano, P., Gracely, R.H., Jain, D., Jarvelin, M.-R., Kaste, L.M., Kerr, K.F., Kocher, T., Lahdesmaki, R., Laniado, N., Laurie, C.C., Laurie, C.A., Mannikko, M., Meloto, C.B., Nackley, A.G., Nelson, S.C., Pesonen, P., Ribeiro-Dasilva, M.C., Rizzatti-Barbosa, C.M., Sanders, A.E., Schwahn, C., Sipila, K., Sofer, T., Teumer, A., Mogil, J.S., Fillingim, R.B., Greenspan, J.D., Ohrbach, R., Slade, G.D., Maixner, W., and Diatchenko, L.  Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males.  Pain, 160:579-591, 2019.   (DOI:  10.1097/j.pain.0000000000001438)
  • Martin, L.J., Acland, E.L., Cho, C., Gandhi, W., Chen, D., Corley, E., Kadoura, B., Levy, T., Mirali, S., Tohyama, S., Khan, S., MacIntyre, L.C., Carlson, E.N., Schweinhardt, P., and Mogil, J.S.  Male-specific conditioned pain hypersensitivity in mice and humans.   Curr. Biol., 29:192-201.e4, 2019.   (DOI:  10.1016/j.cub.2018.11.030) ◊◊◊◊
  • Rosen, S., Ham, B., Haichin, M., Walters, I., Tohyama, S., Sotocinal, S.G., and Mogil, J.S.  Increased pain sensitivity and decreased opioid analgesia in T cell-deficient mice and implications for sex differences.  Pain, 160:358-366, 2019.  (DOI:  10.1097/j.pain.0000000000001420)
  • Baskozos, G., Dawes, J.M., Austin, J.S., Antunes-Martins, A., McDermott, L., Clark, A.J., McMahon, S.B., Mogil, J.S., Orengo, C., and Bennett, D.L.  Comprehensive analysis of long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury.  Pain, 160:463-485, 2019. (DOI:  10.1097/j.pain.0000000000001416)
  • Tansley, S.N., Tuttle, A.H., Wu, N., Tohyama, S., Dossett, K., Gerstein, L., Ham, B., Austin, J.-S., Sotocinal, S.G., and Mogil, J.S.  Modulation of social behavior and dominance status by chronic pain in mice.  Genes Brain Behav., 18:e12514, 2019.   (DOI:  10.1111/gbb.12514)
  • Mapplebeck, J.C.S., Dalgarno, R., Tu, Y.S., Moriarty, O., Beggs, S., Kwok, C.H.T., Halievski, K., Assi, S., Mogil, J.S., Trang, T., and Salter, M.W.  Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats.  Pain, 159:1752-1763, 2018.  (DOI:  10.1097/j.pain.0000000000001265)
  • Uttam, S., Wong, C., Amorim, I.S., Jafarnejad, S.M., Tansley, S.N., Yang, J., Prager?Khoutorsky, M., Mogil, J.S., Gkogkas, C.G., and Khoutorsky, A.  Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain.  Neurobiol. Pain, 4:35-44, 2018.  (DOI:  10.1016/j.ynpai.2018.04.001)
  • Tuttle, A.H., Molinaro, M.J., Jethwa, J.F., Sotocinal, S.G., Prieto, J.C., Styner, M.A., Mogil, J.S., and Zylka, M.J.  A deep neural network to assess spontaneous pain from mouse facial expressions.  Mol. Pain, 14:1-29, 2018.  (DOI:  10.1177/1744806918763658) †◊
  • Rosen, S.F., Ham, B., Drouin, S., Boachie, N., Chabot-Dore, A.-J., Austin, J.-S., Diatchenko, L., and Mogil, J.S.  T cell mediation of pregnancy analgesia affecting chronic pain in mice.   J. Neurosci., 37:9819-9827, 2017.   (DOI:  10.1523/JNEUROSCI.2053-17.2017)
  • Martin, L.J., Smith, S.B., Khoutorsky, A., Magnussen, C.A., Samoshkin, A., Sorge, R.E., Cho, C., Yosefpour, N., Sivaselvachandran, S., Tohyama, S., Cole, T., Khong, T.M., Mir, E., Gibson, D.G., Wieskopf, J.S., Sotocinal, S.G., Austin, J.-S., Meloto, C.B., Gitt, J.H., Gkogkas, C., Sonenberg, N., Greenspan, J., Fillingim, R.B., Ohrbach, R., Slade, G.D., Knott, C., Dubner, R., Nackley, A.G., Ribeiro-da-Silva, A., Neely, G.G., Maixner, W., Zaykin, D.V., Mogil, J.S.*, and Diatchenko, L.*  Epiregulin and EGFR interactions are involved in pain processing.  J. Clin. Invest., 127:3353-3363, 2017.   (*co-corresponding authors)   (DOI:  10.1172/JCI87406) †◊◊◊◊
  • Moy, J.K., Khoutorsky, A., Asiedu, M.N., Black, B.J., Kuh, J.L., Barragan-Iglesias, P., Megat, S., Burton, M.D., Burgos-Vega, C.C., Melemedjian, O.K., Boitano, S., Vagner, J., Gkogkas, C.G., Pancrazio, J.J., Mogil, J.S., Dussor, G., Sonenberg, N., and Price, T.J.     The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain.  J. Neurosci., 37:7481-7499, 2017.   (DOI:  10.1523/JNEUROSCI.0220-17.2017)
  • Parisien, M., Khoury, S., Chabot-Dore, A.-J., Sotocinal, S.G., Slade, G.D., Smith, S.B., Fillingim, R.B., Ohrbach, R., Greenspan, J.D., Maixner, W., Mogil, J.S., Belfer, I., and Diatchenko, L.  Effect of human genetic variability on gene transcription in dorsal root ganglia and association with pain phenotypes.  Cell Rep., 19:1940-1952, 2017.   (DOI:  10.1016/j.celrep.2017.05.018)
  • Tuttle, A.H., Tansley, S., Dossett, K., Tohyama, S., Khoutorsky, A., Maldonado-Bouchard, S., Stein, L., Gerstein, L., Crawhall-Duk, H., Pearl, R., Sukosd, M., Leger, P., Hardt, O., Yachnin, D., Austin, J.-S., Chan, C.M., Groves, I., Pooters, T., Martin, L.J., Sonenberg, N., Gkogkas, C.G., and Mogil, J.S.  Social propinquity in rodents as measured by tube co?occupancy differs between inbred and outbred genotypes.  Proc. Natl. Acad. Sci. U.S.A., 114:5515-5520, 2017.  (DOI:  10.1073/pnas.1703477114)
  • Khoutorsky, A., Sorge, R.E., Prager-Khoutorsky, M., Pawlowski, S.A., Longo, G., Jafarnejad, S.M., Tahmasebi, S., Martin, L.J., Pitcher, M.H., Gkogkas, C.G., Sharif-Naeini, R., Ribeiro-da-Silva, A., Bourque, C.W., Cervero, F., Mogil, J.S.*, and Sonenberg, N.*  eIF2a phosphorylation controls thermal nociception.  Proc. Natl. Acad. Sci., U.S.A., 113:11949-11954, 2016.  (*co-corresponding authors)   (DOI:  10.1073/pnas.1614047113)
  • Ultsch, A., Kringel, D., Kalso, E., Mogil, J.S., and Lotsch, J.  A data science approach to candidate gene selection of pain regarded as a process of learning and neural plasticity.  Pain, 157:2747-2757, 2016.   (DOI: 10.1097/j.pain.0000000000000694)
  • Kikusui, T., Ishio, Y., Nagasawa, M., Mogil, J.S., and Mogi, K.  Early weaning impairs a social contagion of pain-related stretching behavior in mice.  Dev. Psychobiol., 58:1101-1107, 2016.  (DOI:  10.1002/dev.21443)
  • Young, E., Bryant, C., Lee, S., Nair, H., Dreher, K., Zhang, X., Palmer, A., Chung, J.M., Mogil, J.S., Chesler, E., and Lariviere, W.  Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test.  Genes Brain Behav., 15:604-615, 2016.   (DOI:  10.1111/gbb.12302) ◊◊◊
  • Kahle, K.T., Schmouth, J.F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Omura, T., Laganiere, J., Rochefort, D., Hince, P., Castonguay, G., Gaudet, R., Mapplebeck, J.C., Sotocinal, S.G., Duan, J., Ward, C., Khanna, A.R., Mogil, J.S., Dion, P.A., Woolf, C.J., Inquimbert, P., and Rouleau, G.A.  Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition.  Sci. Signal. 9:ra32, 2016.   (DOI:  10.1126/scisignal.aad0163)†
  • Daou, I., Beaudry, H., Ase, A.R., Wieskopf, J.S., Ribeiro-da-Silva, A., Mogil, J.S., and Seguela, P.  Optogenetic silencing of Nav1.8-positive afferents alleviates inflammatory and neuropathic pain.  eNeuro, 3: e0140-15.2016, 2016.   (DOI:  10.1523/ENEURO.0140-15.2016) †◊◊◊
  • Samoshkin, A., Convertino, M., Viet, C.T., Wieskopf, J.S., Marcovitz, J., Patel, P., Stone, L., Maixner, W., Mogil, J.S., Schmidt, B.L., Dokholyan, N.V., and Diatchenko, L.  Structural and functional interaction between six transmembrane m-opioid receptor isoform and b2-adrenoceptors.  Sci. Rep., 5:18198, 2015.   (DOI:  10.1038/srep18198)

  • Khoutorsky, A., Bonin, R.P., Sorge, R.E., Gkogkas, C., Pawlowski, S.A., Jafarnejad, S.M., Pitcher, M.H., Alain, T., Perez-Sanchez, J. Salter, E.W., Martin, L.J., Ribeiro-da-Silva, A., De Koninck, Y., Cervero, F., Mogil, J.S.* and Sonenberg, N.*  Translational control of nociception via 4E-binding protein 1.  eLife, 4:e12002, 2015.  (DOI:  10.7554/eLife.12002)       (*co-corresponding authors)
  • Martin, L.J., Piltonen, M.H., Gauthier, J., Convertino, M., Acland, E.L., Dokholyan, N.V., Mogil, J.S., Diatchenko, L., and Maixner, W.  Differences in the antinociceptive effects and binding properties of propranolol and bupranolol enantiomers.  J. Pain, 16:1321-1333, 2015.   (DOI:  10.1016/j.jpain.2015.09.004)
  • Sorge, R.E., Mapplebeck, J.C.S., Rosen, S., Beggs, S., Taves, S., Alexander, J.K., Martin, L.J., Austin, J.-S., Sotocinal, S.G., Chen, D., Yang, M., Shi, X.Q., Huang, H., Pillon, N.J., Bilan, P.J., Tu, Y., Klip, A., Ji, R.-R., Zhang, J., Salter, M.W. and Mogil, J.S.  Different immune cells mediate mechanical pain hypersensitivity in male and female mice.  Nat. Neurosci., 18:1081-1083, 2015.  (DOI:  10.1038/nn.4053) ♥††††◊◊◊◊◊
  • Segall, S.K., Shabalina, S.A., Meloto, C.B., Wen, X., Gauthier, J., Wiltshire, T., Cunningham, D., Tarantino, L., Tohyama, S., Martin, L.J., Mogil, J.S., and Diatchenko, L.  Molecular genetic mechanisms of allelic specific regulation of murine Comt expression.  Pain, 156:1965-1977, 2015.   (DOI:  10.1097/j.pain.0000000000000258)

  • Wieskopf, J.S., Mathur, J. Limapichat, W., Post, M.R., Al-Qazzaz, M., Sorge, R.E., Martin, L.J., Zaykin, D.V., Smith, S.B., Freitas, K., Austin, J.-S., Dai, F., Zhang, J., Marcovitz, J., Tuttle, A.H., Slepian, P.M., Clarke, S., Drenan, R.M., Janes, J., Al Sharari, S., Segall, S.K., Aasvang, E.K., Lai, W., Bittner, R., Richards, C.I., Slade, G.D., Kehlet, H., Walker, J., Maskos, U., Changeux, J.-P., Devor, M., Maixner, W., Diatchenko, L., Belfer, I., Dougherty, D.A., Su, A.I., Lummis, S.C.R., Damaj, M.I., Lester, H.A., Patapoutian, A., and Mogil, J.S.  The nicotinic a6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.  Sci. Transl. Med., 7:287ra72, 2015.   (DOI: 10.1126/scitranslmed.3009986)
  • Szabo, N.E., da Silva, R.V., Sotocinal, S.G., Zeilhofer, H.U., Mogil, J.S., and Kania, A.  Hoxb8 intersection defines a role for Lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity and nociception.  J. Neurosci., 35:5233-5246, 2015.  (DOI: 10.1523/JNEUROSCI.4690-14.2015) ◊◊
  • Martin, L.J., Hathaway, G., Isbester, K., Mirali, S., Acland, E.L., Niederstrasser, N., Slepian, P.M., Trost, Z., Bartz, J.A., Sapolsky, R.M., Sternberg, W.F., Levitin, D.J., and Mogil, J.S.  Reducing social stress elicits emotional contagion of pain in mouse and human strangers.  Curr. Biol., 25:326-332, 2015.   (DOI: 10.1016/j.cub.2014.11.028) ††◊◊◊◊
  • Cahill, L.S., Laliberte, C.L., Liu, X.J., Bishop, J., Nieman, B.J., Mogil, J.S., Sorge, R.E., Jones, C.D., Salter, M.W., and Henkelman, R.M.  Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse.  Mol. Pain, 10:60, 2014.   (DOI: 10.1186/1744-8069-10-60)
  • Wieskopf, J.S., Pan, Y.-X., Marcovitz, J., Tuttle, A.H., Majumdar, S., Pidakala, J., Pasternak, G.W., and Mogil, J.S.  Broad spectrum analgesic efficacy of IBNtxA is mediated by exon 11-associated splice variants of the mu-opioid receptor gene.  Pain, 155:2063-2070, 2014.   (DOI:10.1016/j.pain.2014.07.014)
  • Tang, S., Ding, Y., Sibille, E. Mogil, J.S., Lariviere, W.R., and Tseng, G.C.  Imputation of truncated p-values for meta-analysis methods and its genomic application.  Ann. Appl. Stat., 8:2150-2174, 2014.   (DOI: 10.1214/14-AOAS747)
  • Sorge, R.E., Martin, L.J., Isbester, K.A., Sotocinal, S.G., Rosen, S., Tuttle, A.H., Wieskopf, J.S., Acland, E.L., Dokova, A., Kadoura, B., Leger, P., Mapplebeck, J.C.S., McPhail, M., Delaney, A., Wigerblad, G., Schumann, A.P., Quinn, T., Frasnelli, J., Svensson, C.I., Sternberg, W.F., and Mogil, J.S.  Olfactory exposure to males, including human males, stresses rodents.  Nat. Meth., 11:629-632, 2014.   (DOI:10.1038/nmeth.2935) ♥††††◊◊◊◊◊
  • Farmer, M.A., Leja, A., Foxen-Craft, E., Chan, L., MacIntyre, L.C., Niaki, T., Chen, M., Mapplebeck, J.C.S., Tabry, V., Topham, L., Sukosd, M., Binik, Y.M., Pfaus, J.G., and Mogil, J.S.  Pain reduces sexual motivation in female but not male mice.  J. Neurosci., 34:5747-5753, 2014.   (DOI:10.1523/JNEUROSCI.5337-13.2014) ◊◊◊
  • Kristiansen, F.L., Olesen, A.E., Brock, C., Gazerani, P., Petrini, L., Mogil, J.S., and Drewes, A.M.  The role of pain catastrophizing in experimental pain perception.  Pain Pract., 14:E136-E145, 2014.   (DOI: 10.1111/papr.12150)
  • Daou, I., Tuttle, A.H., Long, G., Wieskopf, J.S., Bonin, R., Ase, A., Wood, J.N., De Koninck, Y., Ribeiro-da-Silva, A., Mogil, J.S., and Seguela, P.  Remote optogenetic activation and sensitization of pain pathways in freely moving mice.  J. Neurosci., 33:18631-18640, 2013.   (DOI: 10.1523/JNEUROSCI.2424-13.2013) ††
  • Corder, G., Doolen, S., Donahue, R.R., Winter, M.K., Jutras, B.L., He, Y., Hu, X., Wieskopf, J.S., Mogil, J.S., Storm, D.R., Wang, Z.J., McCarson, K.E., and Taylor, B.K.  Constitutive m?opioid receptor activity leads to long-term endogenous analgesia and dependence.  Science, 341:1394-1399, 2013.   (DOI: 10.1126/science.1239403) †††◊◊
  • Belfer, I., Segall, S.K., Lariviere, W.R., Smith, S.B., Dai, F., Slade, G.G., Rashid, N.U., Mogil, J.S., Campbell, C.M., Edwards, R.R., Liu, Q., Bair, E., Maixner, W., and Diatchenko, L.  Pain modality- and sex-specific effects of COMT functional variants.  Pain, 154:1368-1376, 2013.   (DOI: 10.1016/j.pain.2013.04.028) ††
  • Chanda, M.L., Tuttle, A.H., Baran, I., Atlin, C., Guindi, D., Hathaway, G., Israelian, N., Levenstadt, J., Low, D., Macrae, L., O'Shea, L., Silver, A., Zendegui, E., Lenselink, A.M., Spijker, S., Ferrari, M.D., van den Maagdenberg, A.M.J.M., and Mogil, J.S.  Behavioral evidence for photophobia and stress-related ipsilateral head pain in transgenic Cacna1a mutant mice.  Pain, 154:1254-1262, 2013.  (DOI: 10.1016/j.pain.2013.03.038)
  • Melemedjian, O.K., Khoutorsky, A., Sorge, R.E., Yan, J., Asiedu, M.N., Valdez, A., Ghosh, S., Dussor, G., Mogil, J.S., Sonenberg, N., and Price, T.J.  mTORC1 inhibition induces pain via IRS1-dependent feedback activation of ERK.  Pain, 154:1080-1091, 2013.   (DOI: 10.1016/j.pain.2013.03.021)
  • Sorge, R.E., LaCroix-Fralish, M.L., Tuttle, A.H., Khoutorsky, A., Sotocinal, S.G., Austin, J.-S., Melmed, K., Labialle, S., Schmidt, J.V., Wood, J.N., Naumova, A.K., and Mogil, J.S.  The yin and yang of pain: variability in formalin test nociception and morphine analgesia produced by the Yin Yang 1 transcription factor gene.  Genes Brain Behav., 12:405-413, 2013. (DOI: 10.1111/gbb.12030)
  • Khoutorsky, A., Yanagiya, A., Gkogkas, C., Fabian, M.R., Prager-Khoutorsky, M., Cao, R., Gamache, K., Bouthiette, F., Parsyan, A., Sorge, R.E., Mogil, J.S., Nader, K., Lacaille, J.?C., and Sonenberg, N.  Control of synaptic plasticity and memory via suppression of poly(A)-binding protein.  Neuron, 78:298-311, 2013.   (DOI: 10.1016/j.neuron.2013.02.025)
  • Hastie, B.A., Riley, J.L., III, Kaplan, L., Herrera, D.G., Campbell, C.M., Virtusio, K., Mogil, J.S., Wallace, M.R., and Fillingim, R.B.  Ethnicity interacts with the OPRM1 gene in experimental pain sensitivity.  Pain, 153:1610-1619, 2012.  (DOI: 10.1016/j.pain.2012.03.022)
  • Tsao, D., Wieskopf, J.S., Rashid, N., Sorge, R.E., Redler, R.L., Segall, S.K., Mogil, J.S., Maixner, W., Dokholyan, N.V., and Diatchenko, L.  Serotonin-induced hypersensitivity via inhibition of catechol-O-methyltransferase activity.  Mol. Pain, 8:25, 2012.   (DOI: 10.1186/1744-8069-8-25)
  • Malfait, A.M., Seymour, A.B., Gao, F., Tortorella, M.D., Hellio Le Graverand-Gastineau, M.P., Wood, L.S., Doherty, M., Doherty, S., Zhang, W., Arden, N.K., Vaughn, F.L., Leaverton, P.E., Spector, T.D., Hart, D.J., Maciewicz, R.A., Muir, K.R., Das, R., Sorge, R.E., Sotocinal, S.G., Schorscher-Petcu, A., Valdes, A.M., and Mogil, J.S.  A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype.  Ann. Rheum. Dis., 71:1042-1048, 2012.  (DOI:10.1136/annrheumdis-2011-200300)
  • Sorge, R.E., Trang, T., Dorfman, R., Smith, S.B., Beggs, S., Ritchie, J., Austin, J.-S., Zaykin, D.V., Vander Meulen, H., Costigan, M., Herbert, T.A., Yarkoni-Abitbul, M., Tichauer, D., Livneh, J., Gershon, E., Zheng, M., Tan, K., John, S.L., Slade, G.D., Jordan, J., Woolf, C.J., Peltz, G., Maixner, W., Diatchenko, L., Seltzer, Z., Salter, M.W. and Mogil, J.S.  Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.  Nat. Med., 18:595-599, 2012.  (DOI:  10.1038/nm.2710) ††††◊◊◊
  • Shekarabi, M., Moldrich, R., Rasheed, S., Salin-Cantegrel, A., Laganiere, J., Rochefort, D., Hince, P., Huot, K., Gaudet, R., Kurniawan, N., Sotocinal, S.G., Ritchie, J., Dion, P., Mogil, J.S., Richards, L., and Rouleau, G.  Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum.  J. Neurosci., 32:3865-3876, 2012.  (DOI:  10.1523/JNEUROSCI.3679-11.2012) †
  • Matsumiya, L.C., Sorge, R.E., Sotocinal, S.G., Tabaka, J.M., Wieskopf, J.S., Zaloum, A., King, O.D., and Mogil, J.S.  Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice.  J. Am. Assoc. Lab. Anim. Sci., 51:42-49, 2012.   (PMID:  22330867) †††◊
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  • Kest, B., Jenab, S., Brodsky, M., Sadowski, B., Belknap, J.K., Mogil, J.S., and Inturrisi, C.E.  Mu and delta opioid receptor analgesia, binding density, and mRNA levels in mice selectively bred for high and low analgesia.  Brain Res., 816: 381?389, 1999.   (DOI: 10.1016/S0006-8993(98)01141-X)
  • Kest, B., McLemore, G.L., Sadowski, B., Mogil, J.S., Belknap, J.K., and Inturrisi, C.E.  Acute morphine dependence in mice selectively-bred for high and low analgesia.  Neurosci. Lett., 256: 120-122, 1998.  (DOI: 10.1016/S0304-3940(98)00772-1)
  • Kest, B., Beckzowska, I., Franklin, S.O., Lee, C.E., Mogil, J.S., and Inturrisi, C.E.  Differences in delta opioid receptor antinociception, binding, and mRNA levels between BALB/c and CXBK mice.  Brain Res., 805: 131-137, 1998.   (DOI: 10.1016/S0006-8993(98)00696-9)
  • Grisel, J.E., Farrier, D.E., Wilson, S.G., and Mogil, J.S.  [Phe1Y(CH2-NH)Gly2] nociception?(1-13)-NH2 acts as an agonist of the orphanin FQ/nociceptin receptor in vivoEur. J. Pharmacol., 357: R1-R3, 1998.  (DOI: 10.1016/S0014-2999(98)00567-6)
  • Mogil, J.S., Lichtensteiger, C.A., and Wilson, S.G.  The effect of genotype on sensitivity to inflammatory nociception: characterization of resistant (A/J) and sensitive (C57BL/6J) inbred mouse strains.  Pain, 76: 115-125, 1998.  (DOI: 10.1016/S0304-3959(98)00032-3)
  • Mogil, J.S., Shin, Y.-H., McCleskey, E.W., Kim, S.-C., and Nah, S.-Y.  Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice.  Brain Res., 792: 218?228, 1998.  (DOI: 10.1016/S0006-8993(98)00133-4) ††
  • Sufka, K.J., Watson, G.S., Nothdurft, R.E., and Mogil, J.S.  Scoring the mouse formalin test: validation study.  Eur. J. Pain, 2: 351-358, 1998.  (DOI: 10.1016/S1090-3801(98)90033-7)
  • Mogil, J.S. and Wilson, S.G.  Nociceptive and morphine antinociceptive sensitivity of 129 and C57BL/6 inbred mouse strains: implications for transgenic knock-out studies.  Eur. J. Pain, 1: 293-297, 1997.  (DOI: 10.1016/S1090-3801(97)90038-0)
  • Mogil, J.S., Richards, S.P., O'Toole, L.A., Mitchell, S.R., Helms, M.L., Kest, B., and Belknap, J.K.  Identification of sex-specific quantitative trait loci mediating non-opioid swim stress-induced analgesia in female mice.  J. Neurosci., 17: 7995?8002, 1997.  (DOI:  10.1523/JNEUROSCI.17-20-07995.1997) ††
  • Mogil, J.S., Richards, S.P., O'Toole, L.A., Helms, M.L., Mitchell, S.R., and Belknap, J.K.  Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by d2-opioid receptors.  Pain, 70: 267-277, 1997.   (DOI: 10.1016/S0304-3959(97)03333-2) †††
  • Tian, J.-H., Xu, W., Fang, Y., Mogil, J.S., Grisel, J.E., Grandy, D.K., and Han, J.-S.  Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat.  Br. J. Pharmacol., 120: 676-680, 1997.  (DOI: 10.1038/sj.bjp.0700942) ††††
  • Kest, B., Lee, C.E., Mogil, J.S., and Inturrisi, C.E.  Blockade of morphine supersensitivity by an antisense oligodeoxynucleotide targeting the delta opioid receptor (DOR-1).  Life Sci., 60: PL155-159, 1997.  (DOI: 10.1016/S0024-3205(96)00704-7)
  • Tian, J.-H., Xu, W., Fang, Y., Grisel, J.E., Mogil, J.S., Grandy, D.K., and Han, J.-S.  Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia.  Neuroreport, 8: 497-500, 1997.  (DOI: 10.1097/00001756-199701200-00024) ††
  • Mogil, J.S. and Belknap, J.K.  Sex and genotype determine the selective activation of neurochemically-distinct forms of swim stress-induced analgesia.  Pharmacol. Biochem. Behav., 56: 61-66, 1997.  (DOI: 10.1016/S0091-3057(96)00157-8) ††
  • Mogil, J.S., Grisel, J.E., Reinscheid, R.K., Civelli, O., Belknap, J.K., and Grandy, D.K.  Orphanin FQ is a functional anti-opioid peptide.  Neuroscience, 75: 333-337, 1996.   (DOI: 10.1097/00001756-199609020-00012) ††††
  • Grisel, J.E., Mogil, J.S., Belknap, J.K., and Grandy, D.K.  Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide.  Neuroreport, 7: 2125-2129, 1996.   (DOI: 10.1097/00001756-199609020-00012) †††
  • Mogil, J.S., Grisel, J.E., Zhang, G., Belknap, J.K., and Grandy, D.K.  Functional antagonism of m-, δ- and κ-opioid antinociception by orphanin FQ.  Neurosci. Lett., 214: 131-134, 1996.  (DOI: 10.1016/0304-3940(96)12917-7) †††
  • Rubinstein, M.*, Mogil, J.S.*, Japón, M., Chan, E.C., Allen, R.G., and Low, M.J.  Absence of opioid stress-induced analgesia in mice lacking b-endorphin by site-directed mutagenesis.  Proc. Natl. Acad. Sci., USA, 93: 3995-4000, 1996.  (*co-first authors)  (DOI: 10.1073/pnas.93.9.3995) ††††
  • Mogil, J.S., Kest, B., Sadowski, B., and Belknap, J.K.  Differential genetic mediation of sensitivity to morphine in genetic models of opiate sensitivity: influence of nociceptive assay.  J. Pharmacol. Exp. Ther., 276: 532-544, 1996.  (PMID:  8632319) †††
  • Mogil, J.S., Sternberg, W.F., Balian, H., Liebeskind, J.C., and Sadowski, B.  Opioid and non?opioid swim stress-induced analgesia: a parametric analysis in mice.  Physiol. Behav., 59: 123-132, 1996.  (DOI: 10.1016/0031-9384(95)02073-X) †††
  • Kest, B., Brodsky, M., Sadowski, B., Mogil, J.S., and Inturrisi, C.E.  Mu-opiate receptor (Mor-1) mRNA levels are altered in mice with differential analgesic sensitivity to the mu agonist, DAMGO.  Analgesia, 1: 498-501, 1995.  (not MEDLINE indexed)
  • Sternberg, W.F., Mogil, J.S., Kest, B., Page, G.G., Leong, Y., Yam, V., and Liebeskind, J.C.  Neonatal testosterone exposure influences neurochemistry of swim stress-induced analgesia in adult mice.  Pain, 63: 321-326, 1995.  (DOI: 10.1016/0304-3959(95)00059-3) ††
  • Mogil, J.S., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines.  Behav. Genet., 25: 397-406, 1995.  (DOI: 10.1007/BF02197290)
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C.  1,3-di-o-tolylguanidine (DTG) differentially affects acute and tonic formalin pain: antagonism by rimcazole.  Pharmacol. Biochem. Behav., 52: 175-178, 1995.   (DOI: 10.1016/0091-3057(95)00085-B)
  • Vaccarino, F.J., Mogil, J.S., and Stinus, L.  Chronic dopamine antagonism facilitates opiate?induced feeding.  J. Psychiat. Neurosci., 20: 210-214, 1995.  (PMID:  7786882) 
  • Belknap, J.K., Mogil, J.S., Helms, M.L., O'Toole, L.A., Richards, S.P., and Bergeson, S.E.  Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/6 and DBA/2 mouse strains.  Life Sci., 57: PL117-124, 1995.   (DOI:  10.1016/0024-3205(95)02040-P) ††
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C.  Antinociception following 1,3-di-o-tolylguanidine (DTG), a selective sigma receptor ligand.  Pharmacol. Biochem. Behav., 50: 587-592, 1995.   (DOI: 10.1016/0091-3057(94)00346-7)
  • Mogil, J.S., Marek, P., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., and Liebeskind, J.C.  One or two genetic loci mediate high opiate analgesia in selectively bred mice.  Pain, 60: 125-135, 1995.  (DOI: 10.1016/0304-3959(94)00098-Y)
  • Mogil, J.S., Marek, P., O'Toole, L.A., Helms, M.L., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia.  Brain Res., 653: 16-22, 1994.   (DOI: 10.1016/0006-8993(94)90366-2) ††
  • Mogil, J.S., Sternberg, W.F., Kest, B., Marek, P., and Liebeskind, J.C.  Sex differences in the antagonism of swim stress-induced analgesia: effects of gonadectomy and estrogen replacement.  Pain, 253: 17-25, 1993.  (DOI: 10.1016/0304-3959(93)90050-Y) ††††
  • Marek, P., Mogil, J.S., Belknap, J.K., Sadowski, B., and Liebeskind, J.C.  Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalties.  Brain Res., 608: 353-357, 1993.  (DOI: 10.1016/0006-8993(93)91479-C)
  • Mogil, J.S., Marek, P., Yirmiya, R., Balian, H., Sadowski, B., Taylor, A.N., and Liebeskind, J.C.  Antagonism of the non-opioid component of ethanol-induced analgesia by the NMDA receptor antagonist MK-801.  Brain Res., 602: 126-130, 1993.   (DOI: 10.1016/0006-8993(93)90251-H)
  • Marek, P., Mogil, J.S., Sternberg, W.F., Panocka, I., and Liebeskind, J.C.  N?Methyl-D-aspartic acid (NMDA) receptor antagonist MK-801 blocks non-opioid stress-induced analgesia.  II. Studies using three different water temperature paradigms and selectively bred mice.  Brain Res., 578: 197-203, 1992.  (DOI: 10.1016/0006-8993(92)90248-8) ††
  • Ben-Eliyahu, S., Marek, P., Vaccarino, A.L., Mogil, J.S., Sternberg, W.F., and Liebeskind, J.C.  The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat.  Brain Res., 575: 304-308, 1992.  (DOI: 10.1016/0006-8993(92)90094-P) †††

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